Edmund J. Moran: search on Z-Library

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1

A 28-day, randomized, double-blind, placebo-controlled, parallel group study of nebulized revefenacin in patients with chronic obstructive pulmonary disease

Pudi, Krishna K., Barnes, Chris N., Moran, Edmund J., Haumann, Brett, Kerwin, Edward

Journal:

Respiratory Research

Year:

2017

Language:

english

File:

PDF, 752 KB

english, 2017

2

Highly convergent approach to the synthesis of the epoxy-amide fragment of the azinomycins

Edmund J. Moran, Robert W. Armstrong

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 251 KB

english, 1991

3

Synthetic studies towards carzinophilin: Synthesis and ammonium hydroxide-induced rearrangement of the epoxi-acid fragment

Pamela England, Ho Chun Keun, Edmund J. Moran, Robert W. Armstrong

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 240 KB

english, 1990

4

PDLIM2 is a marker of adhesion and β-catenin activity in triple-negative breast cancer

Cox, Orla T, Edmunds, Shelley J, Simon-Keller, Katja, Li, Bo, Moran, Bruce, Buckley, Niamh E, Bustamante-Garrido, Milan, Healy, Nollaig, O'Flanagan, Ciara H, Gallagher, William M, Kennedy, Richard D,

Journal:

Cancer Research

Year:

2019

Language:

english

File:

PDF, 5.28 MB

english, 2019

5

Data on the safety and tolerability of revefenacin, in patients with moderate to very severe chronic obstructive pulmonary disease

Donohue, James, Kerwin, Edward, Sethi, Sanjay, Haumann, Brett, Pendyala, Srikanth, Dean, Lorna, Barnes, Chris N., Moran, Edmund J., Crater, Glenn

Journal:

Year:

2019

Language:

english

File:

PDF, 498 KB

english, 2019

6

Mono-osmylation of dehydroamino acid dienes: synthesis of dehydroamino acids related to the azinomycins

Robert W Armstrong, John E Tellew, Edmund J Moran

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 198 KB

english, 1996

7

2,4,5-Trisubstituted imidazoles: novel nontoxic modulators of P-glycoprotein mediated multidrug resistance. Part 1

Sepehr Sarshar, Chengzhi Zhang, Edmund J. Moran, Sonja Krane, Jennifer C. Rodarte, Khalid D. Benbatoul, Ross Dixon, Adnan M.M. Mjalli

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 113 KB

english, 2000

8

TOLERABILITY AND EFFICACY OF REVEFENACIN WHEN ADMINISTERED WITH FORMOTEROL VIA NEBULIZATION

Siler, Thomas, Moran, Edmund, Yun, Jang, Barnes, Chris, Crater, Glenn

Journal:

Year:

2019

Language:

english

File:

PDF, 98 KB

english, 2019

9

2,4,5-Trisubstituted imidazoles: novel nontoxic modulators of P-glycoprotein mediated multidrug resistance. Part 2

Chengzhi Zhang, Sepehr Sarshar, Edmund J. Moran, Sonja Krane, Jennifer C. Rodarte, Khalid D. Benbatoul, Ross Dixon, Adnan M.M. Mjalli

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 113 KB

english, 2000

10

PDLIM2 is a marker of adhesion and β-catenin activity in triple-negative breast cancer

Cox, Orla T, Edmunds, Shelley J, Simon-Keller, Katja, Li, Bo, Moran, Bruce, Buckley, Niamh E, Bustamante-Garrido, Milan, Healy, Nollaig, O'Flanagan, Ciara H, Gallagher, William M, Kennedy, Richard D,

Journal:

Cancer Research

Year:

2019

File:

PDF, 5.28 MB

2019

11

The 24-Hour Profile of FEV 1 After 12-Weeks Treatment With Revefenacin, a Once Daily Long-Acting Muscarinic Receptor Antagonists for Nebulization: A Spirometry Substudy

Donohue, James, Pendyala, Srikanth, Barnes, Chris, Moran, Edmund, Crater, Glenn

Journal:

Year:

2017

Language:

english

File:

PDF, 74 KB

english, 2017

12

Efficacy of revefenacin, a long-acting muscarinic antagonist for nebulized therapy, in patients with markers of more severe COPD: a post hoc subgroup analysis

Donohue, James F., Kerwin, Edward, Barnes, Chris N., Moran, Edmund J., Haumann, Brett, Crater, Glenn D.

Journal:

BMC Pulmonary Medicine

Year:

2020

File:

PDF, 807 KB

2020

13

Simplified method for the isolation of thermally labile drug-DNA adducts: Characterization of chlorambucil and carzinophilin/azinomycin B alkylation products

Mark E. Salvati, Edmund J. Moran, Robert W. Armstrong

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 292 KB

english, 1992

14

Radio Frequency Tag Encoded Combinatorial Library Method for the Discovery of Tripeptide-Substituted Cinnamic Acid Inhibitors of the Protein Tyrosine Phosphatase PTP1B

Moran, Edmund J., Sarshar, Sepehr, Cargill, John F., Shahbaz, Manouchehr M., Lio, Anna, Mjalli, Adnan M. M., Armstrong, Robert W.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 1.04 MB

english, 1995

15

Trials in Progress: Two 12-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 3 Trials of a Nebulized Long-Acting Muscarinic Antagonist (Revefenacin) in Study Participants With Moderate to Very Severe COPD

Pudi, Krishna, Pendyala, Srikanth, Barnes, Chris, Moran, Edmund, Haumann, Brett, Kerwin, Edward

Journal:

Year:

2016

Language:

english

File:

PDF, 102 KB

english, 2016

16

Stereoselective synthesis of a 1-azabicyclo[3.1.0]hex-2-ylidene dehydroamino acid derivative related to the azinomycin antitumor antibiotics

Armstrong, Robert W., Moran, Edmund J.

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 271 KB

english, 1992

17

Vancomycin Cerebrospinal Fluid Pharmacokinetics in Children with Cerebral Ventricular Shunt Infections

Autmizguine, Julie, Moran, Cassie, Gonzalez, Daniel, Capparelli, Edmund V., Smith, P. Brian, Grant, Gerald A, Benjamin, Daniel K., Cohen-Wolkowiez, Michael, Watt, Kevin M.

Journal:

Pediatric Infectious Disease Journal

Year:

2014

Language:

english

File:

PDF, 213 KB

english, 2014

18

Improvements in Health Status With Revefenacin, a Once-Daily Long-Acting Muscarinic Antagonist for Nebulization: Changes in St George’s Respiratory Questionnaire and COPD Assessment Test in Replicate 3-Month Studies

Donohue, James, Pendyala, Srikanth, Barnes, Chris, Moran, Edmund, Crater, Glenn

Journal:

Year:

2017

Language:

english

File:

PDF, 75 KB

english, 2017

19

Safety and pharmacokinetics of multiple-dose anidulafungin in infants

Michael Cohen-Wolkowiez, Brian Smith⁎, Lauren Piper, Cassie Moran, Ping Liu, Angela Kashuba, Edmund Capparelli, Thomas Walsh, William Hope, Daniel K. Benjamin Jr.

Journal:

Early Human Development

Year:

2009

Language:

english

File:

PDF, 56 KB

english, 2009

20

Synthesis and pharmacological activity of angiotensin-converting enzyme inhibitors: N-(mercaptoacyl)-4-substituted-(S)-prolines

Smith, Elizabeth M., Swiss, Gerald F., Neustadt, Bernard R., Gold, Elijah H., Sommer, Jane A., Brown, Arthur D., Chiu, Peter J. S., Moran, Rosa, Sybertz, Edmund J., Baum, Thomas

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 1.36 MB

english, 1988

21

Maintained therapeutic effect of revefenacin over 52 weeks in moderate to very severe Chronic Obstructive Pulmonary Disease (COPD)

Donohue, James F., Kerwin, Edward, Sethi, Sanjay, Haumann, Brett, Pendyala, Srikanth, Dean, Lorna, Barnes, Chris N., Moran, Edmund J., Crater, Glenn

Journal:

Respiratory Research

Year:

2019

Language:

english

File:

PDF, 1.06 MB

english, 2019

22

TD-8236, a lung-selective inhaled pan-JAK inhibitor, inhibits gene expression related to severe asthma and exhaled nitric oxide (FeNO), in 3-D airway epithelium liquid interface (ALI) cultures derived from asthmatic donors

Kaufman, Elad, Kleinschek, Melanie, Moran, Edmund, Woo, Jacky, Sana, Reuben, Gordon, Emma, Lee, Wanju, Crater, Glenn, Southworth, Thomas, Scott, Thomas, Singh, Dave, Pfeiffer, Nathan

Journal:

Journal of Allergy and Clinical Immunology

Year:

2020

File:

PDF, 124 KB

2020

23

A Multivalent Approach to Drug Discovery for Novel Antibiotics

Long, Daniel D, Aggen, James B, Christensen, Burton G, Judice, J Kevin, Hegde, Sharath S, Kaniga, Koné, Krause, Kevin M, Linsell, Martin S, Moran, Edmund J, Pace, John L

Journal:

The Journal of Antibiotics

Year:

2008

Language:

english

File:

PDF, 163 KB

english, 2008

24

Dehydroamino acid derivatives from D-arabinose and L-serine: synthesis of models for the azinomycin antitumor antibiotics

Moran, Edmund J., Tellew, John E., Zhao, Zuchun, Armstrong, Robert W.

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 1.59 MB

english, 1993

25

Duration by Design: Discovery of Revefenacin, the First-in-Class Nebulized Once-Daily Bronchodilator for the Treatment of Patients With COPD

Ji, Yuhua, Husfeld, Craig, Pulido-Rios, M. Teresa, McNamara, Alexander, Obedencio, Glenmar P., Baldwin, Mike, Bourdet, David, Hegde, Sharath, Mammen, Mathai, Moran, Edmund

Journal:

Year:

2016

Language:

english

File:

PDF, 99 KB

english, 2016

26

EFFICACY OF REVEFENACIN BY NEBULIZATION AND TIOTROPIUM BY HANDIHALER IN SUBJECTS WITH COPD AND SUBOPTIMAL PEAK INSPIRATORY FLOW RATES (PIFR)

MAHLER, DONALD, OHAR, JILL, BARNES, CHRIS, MORAN, EDMUND, PENDYALA, SRIKANTH, CRATER, GLENN

Journal:

Year:

2018

Language:

english

File:

PDF, 99 KB

english, 2018

27

EFFICACY OF REVEFENACIN, A LONG-ACTING MUSCARINIC ANTAGONIST FOR NEBULIZED THERAPY, IN COPD PATIENTS WITH MARKERS OF MORE SEVERE DISEASE

DONOHUE, JAMES, KERWIN, EDWARD, BARNES, CHRIS, MORAN, EDMUND, HAUMANN, BRETT, PENDYALA, SRIKANTH, CRATER, GLENN

Journal:

Year:

2018

Language:

english

File:

PDF, 97 KB

english, 2018

28

Revefenacin, a once-daily, lung-selective, long-acting muscarinic antagonist for nebulized therapy: Safety and tolerability results of a 52-week phase 3 trial in moderate to very severe chronic obstructive pulmonary disease

Donohue, James F., Kerwin, Edward, Sethi, Sanjay, Haumann, Brett, Pendyala, Srikanth, Dean, Lorna, Barnes, Chris N., Moran, Edmund J., Crater, Glenn

Journal:

Respiratory Medicine

Year:

2019

Language:

english

File:

PDF, 729 KB

english, 2019

29

Synthesis of Nh-acyl-α-aminoamides on rink resin: Inhibitors of the hematopoietic protein tyrosine phosphatase (HePTP)

Xiaodong Cao, Edmund J. Moran, Daniel Siev, Anna Lio, Cara Ohashi, Adnan M.M. Mjalli

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 264 KB

english, 1995

30

A multivalent approach to the discovery of long-acting β2-adrenoceptor agonists for the treatment of asthma and COPD

John R. Jacobsen, Seok Ki Choi, Jesse Combs, Eric J.L. Fournier, Uwe Klein, Juergen W. Pfeiffer, G. Roger Thomas, Cecile Yu, Edmund J. Moran

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 838 KB

english, 2012

31

Synthesis of tetrasubstituted imidazoles via α-(N-acyl-N-alkylamino)-β-ketoamides on Wang resin

Chengzhi Zhang, Edmund J Moran, Thomas F Woiwode, Kevin M Short, Adnan M.M Mjalli

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 209 KB

english, 1996

32

Novel biopolymers for drug discovery

Edmund J. Moran, Troy E. Wilson, Charles Y. Cho, Sara R. Cherry, Peter G. Schultz

Journal:

Year:

1995

Language:

english

File:

PDF, 673 KB

english, 1995

33

Stereoselective synthesis of (E)- and (Z)-1-azabicyclo[3.1.0]hex-2-ylidene dehydroamino acid derivatives

Armstrong, Robert W., Tellew, John E., Moran, Edmund J.

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 853 KB

english, 1992

34

Influence of Angiotensin Converting Enzyme Inhibition with Captopril on Blood Pressure and Adrenergic Function in Normal and Sodium Restricted Rats

Sybertz, Edmund J., Sabin, Crawford S., Moran, Rosa

Journal:

Clinical and Experimental Hypertension

Year:

1981

Language:

english

File:

PDF, 900 KB

english, 1981

35

Computer Use in Documentation and Clinical Practice

Moran, Michael, Kosmahl, Edmund, Brimer, Mark

Journal:

Topics in Geriatric Rehabilitation

Year:

1997

File:

PDF, 374 KB

1997

36

Trial in Progress: A 52-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 3 Trial to Evaluate the Safety and Tolerability of a Nebulized Long-Acting Muscarinic Antagonist (Revefenacin) in Study Participants With COPD

DeLaCruz, Luis, Pendyala, Srikanth, Barnes, Chris, Moran, Edmund, Haumann, Brett, Feldman, Gregory

Journal:

Year:

2016

Language:

english

File:

PDF, 101 KB

english, 2016

37

Patient characteristics and outcomes of a hip fracture and concomitant fracture compared with hip fracture alone: results from a United Kingdom teaching hospital

Ong, Terence, Anand, Varun, Tan, Wei, Quah, Edmund, Moran, Chris, Sahota, Opinder

Journal:

Archives of Orthopaedic and Trauma Surgery

Year:

2016

Language:

english

File:

PDF, 344 KB

english, 2016

38

Nebulized Revefenacin Results in a Reduction in the Daily Use of Rescue Medication: Results From a 28-Day Study in Participants With COPD

Pudi, Krishna, Barnes, Chris, Moran, Edmund, Haumann, Brett, Kerwin, Edward

Journal:

Year:

2016

Language:

english

File:

PDF, 102 KB

english, 2016

39

ChemInform Abstract: 2,4,5-Trisubstituted Imidazoles: Novel Nontoxic Modulators of P-Glycoprotein Mediated Multidrug Resistance. Part 1.

Sepehr Sarshar, Chengzhi Zhang, Edmund J. Moran, Sonja Krane, Jennifer C. Rodarte, Khalid D. Benbatoul, Ross Dixon, Adnan M. M. Mjalli

Journal:

Year:

2001

File:

PDF, 28 KB

2001

40

Application of the revised lung cancer staging system (IASLC Staging Project) to a cancer center population

Edmund S. Kassis, Ara A. Vaporciyan, Stephen G. Swisher, Arlene M. Correa, B. Nebiyou Bekele, Jeremy J. Erasmus, Wayne L. Hofstetter, Ritsuko Komaki, Reza J. Mehran, Cesar A. Moran, Katherine M. Piste

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2009

Language:

english

File:

PDF, 338 KB

english, 2009

41

ChemInform Abstract: 2,4,5-Trisubstituted Imidazoles: Novel Nontoxic Modulators of P-Glycoprotein Mediated Multidrug Resistance. Part 2.

Chengzhi Zhang, Sepehr Sarshar, Edmund J. Moran, Sonja Krane, Jennifer C. Rodarte, Khalid D. Benbatoul, Ross Dixon, Adnan M. M. Mjalli

Journal:

Year:

2001

File:

PDF, 28 KB

2001

42

Intravenous fluid loading with or without supplementary dextrose does not prevent nausea, vomiting and pain after laparoscopy

Conan McCaul, Ciaran Moran, Donal O’Cronin, Finola Naughton, Michael Geary, Edmund Carton, James Gardiner

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

2003

File:

PDF, 195 KB

2003

43

Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD

McKinnell, R. Murray, Klein, Uwe, Linsell, Martin S., Moran, Edmund J., Nodwell, Matthew B., Pfeiffer, Juergen W., Thomas, G. Roger, Yu, Cecile, Jacobsen, John R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

44

Pharmacodynamics, pharmacokinetics and safety of revefenacin (TD-4208), a long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD): Results of two randomized, double-blind, phase 2 studies

Quinn, Dean, Barnes, Christopher N., Yates, Wayne, Bourdet, David L., Moran, Edmund J., Potgieter, Peter, Nicholls, Andrew, Haumann, Brett, Singh, Dave

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

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